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KMID : 0359719940120020311
Journal of the Korean Neurological Association
1994 Volume.12 No. 2 p.311 ~ p.316
Technetium-99m DTPA Partition Test in Differential Diagnosis of Tuberculous Meningitis
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Abstract
The utility of the radioactive technetium-99m DTPA partitio test in differentiating tuberculous meningitis from aseptic meningitis was assessed. The test was carried out in 20 patients with tuberculous meningitis, 12 patients with aseptic
meningitis and
10 normal controls.
The accuracy, sensitivity and specificity of the 99mTc-DTPA partition test found to be 86.9%, 100T and 86.4% rspectively if a critical serum/CSF ratio of 2.5 was chosen. In all of the tuberculous cases the serum/CSF radioactive technetium ratio
was
below the critical value of 2.5, while the ration was above this value in nine of twelve cases of aseptic meningitis and all of the normal controls.
This result indicates that the radioactive 99mTc-DTPA partition test is a simple and useful one in the differential diagnosis of early state of tuberculous meningitis from other lymphocytic meningitis
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